I'll leave the forwards up to discussion, but as far as the halves are concerned a lot of people seem to think either Anasta or Mullen are the answer.
If you play Mullen, you've got a young halves combo of the future, with without a lot of experience....which could be dangerous if they're opposite Thurston, Lockyer and/or Prince.
If you put Anasta at 5/8th then, is it worth giving Pearce a shot? I've seen those two pull off three or four different plays where they are both involved. It's like they've got some kind of psychic connection. I can't see Anasta developing that with any other halfback in the space of a week.
I reckon thats the way to go. Anasta has experience and is in career-best form, Pearce will definitely play origin someday, might as well be sooner rather than later.